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Antibody-Mediated Protection against Cryptococcus neoformans Pulmonary Infection Is Dependent on B Cells

The pathogenesis of pulmonary Cryptococcus neoformans infection and the efficacy of passive immunoglobulin G1 (IgG1) administration were investigated in B-cell-deficient and C57BL/6J mice. C57BL/6J mice lived longer than B-cell-deficient mice after both intratracheal and intravenous infections. Admi...

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Autores principales: Rivera, Johanna, Zaragoza, Oscar, Casadevall, Arturo
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Microbiology 2005
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC546959/
https://ncbi.nlm.nih.gov/pubmed/15664957
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.73.2.1141-1150.2005
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