The CSF Immune Response in HIV-1–Associated Cryptococcal Meningitis: Macrophage Activation, Correlates of Disease Severity, and Effect of Antiretroviral Therapy

BACKGROUND: Immune modulation may improve outcome in HIV-associated cryptococcal meningitis. Animal studies suggest alternatively activated macrophages are detrimental but human studies are limited. We performed a detailed assessment of the cerebrospinal fluid (CSF) immune response and examined immu...

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Pubblicato in:J Acquir Immune Defic Syndr
Autori principali: Scriven, James E., Graham, Lisa M., Schutz, Charlotte, Scriba, Thomas J., Wilkinson, Katalin A., Wilkinson, Robert J., Boulware, David R., Urban, Britta C., Meintjes, Graeme, Lalloo, David G.
Natura: Artigo
Lingua:Inglês
Pubblicazione: JAIDS Journal of Acquired Immune Deficiency Syndromes 2017
Soggetti:
Clinical Science
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5469563/
https://ncbi.nlm.nih.gov/pubmed/28346317
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/QAI.0000000000001382
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