Genome-Wide Screening Uncovers the Significance of N-Sulfation of Heparan Sulfate as a Host Cell Factor for Chikungunya Virus Infection

The molecular mechanisms underlying chikungunya virus (CHIKV) infection are poorly characterized. In this study, we analyzed the host factors involved in CHIKV infection using genome-wide screening. Human haploid HAP1 cells, into which an exon-trapping vector was introduced, were challenged with a v...

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Vydáno v:J Virol
Hlavní autoři: Tanaka, Atsushi, Tumkosit, Uranan, Nakamura, Shota, Motooka, Daisuke, Kishishita, Natsuko, Priengprom, Thongkoon, Sa-ngasang, Areerat, Kinoshita, Taroh, Takeda, Naokazu, Maeda, Yusuke
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Microbiology 2017
Témata:
Virus-Cell Interactions
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5469253/
https://ncbi.nlm.nih.gov/pubmed/28404855
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00432-17
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