Genome-Wide Screening Uncovers the Significance of N-Sulfation of Heparan Sulfate as a Host Cell Factor for Chikungunya Virus Infection

The molecular mechanisms underlying chikungunya virus (CHIKV) infection are poorly characterized. In this study, we analyzed the host factors involved in CHIKV infection using genome-wide screening. Human haploid HAP1 cells, into which an exon-trapping vector was introduced, were challenged with a v...

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Detalhes bibliográficos
Publicado no:J Virol
Main Authors: Tanaka, Atsushi, Tumkosit, Uranan, Nakamura, Shota, Motooka, Daisuke, Kishishita, Natsuko, Priengprom, Thongkoon, Sa-ngasang, Areerat, Kinoshita, Taroh, Takeda, Naokazu, Maeda, Yusuke
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2017
Assuntos:
Virus-Cell Interactions
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5469253/
https://ncbi.nlm.nih.gov/pubmed/28404855
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00432-17
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