PD134308, a selective antagonist of cholecystokinin type B receptor, enhances the analgesic effect of morphine and synergistically interacts with intrathecal galanin to depress spinal nociceptive reflexes.

The effects of systemic PD134308 [0.1-3 mg/kg; an antagonist of the cholecystokinin (CCK) type B receptor], morphine, and intrathecal (i.t.) galanin (GAL) on the excitability of the spinal nociceptive flexor reflex and in the hot plate test were examined in rats. PD134308 caused a weak naloxone-reve...

ver descrição completa

Detalhes bibliográficos

Publicado no:	Proc Natl Acad Sci U S A
Principais autores:	Wiesenfeld-Hallin, Z, Xu, X J, Hughes, J, Horwell, D C, Hökfelt, T
Formato:	Artigo
Idioma:	Inglês
Publicado em:	National Academy of Sciences 1990
Assuntos:	Research Article
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC54692/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1698290/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.87.18.7105
Tags:	Adicionar Tag Sem tags, seja o primeiro a adicionar uma tag!