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Antiangiogenic agents targeting different angiogenic pathways have opposite effects on tumor hypoxia in R-18 human melanoma xenografts

BACKGROUND: Studies comparing the effect of antiangiogenic agents targeting different angiogenic pathways are sparse. The purpose of this study was to compare the effect of properdistatin and sunitinib treatment in a preclinical model of malignant melanoma. Properdistatin is a small peptide derived...

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Detalhes bibliográficos
Publicado no:BMC Cancer
Main Authors: Gaustad, Jon-Vidar, Simonsen, Trude G., Andersen, Lise Mari K., Rofstad, Einar K.
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5469039/
https://ncbi.nlm.nih.gov/pubmed/28606060
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12885-017-3404-4
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