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Sunitinib treatment does not improve blood supply but induces hypoxia in human melanoma xenografts
BACKGROUND: Antiangiogenic agents that disrupt the vascular endothelial growth factor pathway have been demonstrated to normalize tumor vasculature and improve tumor oxygenation in some studies and to induce hypoxia in others. The aim of this preclinical study was to investigate the effect of suniti...
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| Auteurs principaux: | , , , |
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| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
BioMed Central
2012
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3489843/ https://ncbi.nlm.nih.gov/pubmed/22947392 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2407-12-388 |
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