Suppression of experimental cerebral malaria by disruption of malate:quinone oxidoreductase

BACKGROUND: Aspartate, which is converted from oxaloacetate (OAA) by aspartate aminotransferase, is considered an important precursor for purine salvage and pyrimidine de novo biosynthesis, and is thus indispensable for the growth of Plasmodium parasites at the asexual blood stages. OAA can be produ...

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Bibliografske podrobnosti
izdano v:Malar J
Main Authors: Niikura, Mamoru, Komatsuya, Keisuke, Inoue, Shin-Ichi, Matsuda, Risa, Asahi, Hiroko, Inaoka, Daniel Ken, Kita, Kiyoshi, Kobayashi, Fumie
Format: Artigo
Jezik:Inglês
Izdano: BioMed Central 2017
Teme:
Research
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC5469008/
https://ncbi.nlm.nih.gov/pubmed/28606087
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12936-017-1898-5
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