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Suppression of experimental cerebral malaria by disruption of malate:quinone oxidoreductase
BACKGROUND: Aspartate, which is converted from oxaloacetate (OAA) by aspartate aminotransferase, is considered an important precursor for purine salvage and pyrimidine de novo biosynthesis, and is thus indispensable for the growth of Plasmodium parasites at the asexual blood stages. OAA can be produ...
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| Publié dans: | Malar J |
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| Auteurs principaux: | , , , , , , , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
BioMed Central
2017
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5469008/ https://ncbi.nlm.nih.gov/pubmed/28606087 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12936-017-1898-5 |
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