Suppression of experimental cerebral malaria by disruption of malate:quinone oxidoreductase

BACKGROUND: Aspartate, which is converted from oxaloacetate (OAA) by aspartate aminotransferase, is considered an important precursor for purine salvage and pyrimidine de novo biosynthesis, and is thus indispensable for the growth of Plasmodium parasites at the asexual blood stages. OAA can be produ...

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Enregistré dans:
Détails bibliographiques
Publié dans:Malar J
Auteurs principaux: Niikura, Mamoru, Komatsuya, Keisuke, Inoue, Shin-Ichi, Matsuda, Risa, Asahi, Hiroko, Inaoka, Daniel Ken, Kita, Kiyoshi, Kobayashi, Fumie
Format: Artigo
Langue:Inglês
Publié: BioMed Central 2017
Sujets:
Research
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5469008/
https://ncbi.nlm.nih.gov/pubmed/28606087
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12936-017-1898-5
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