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Dissecting BMP signaling input into the gene regulatory networks driving specification of the blood stem cell lineage

Hematopoietic stem cells (HSCs) that sustain lifelong blood production are created during embryogenesis. They emerge from a specialized endothelial population, termed hemogenic endothelium (HE), located in the ventral wall of the dorsal aorta (DA). In Xenopus, we have been studying the gene regulato...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Main Authors: Kirmizitas, Arif, Meiklejohn, Stuart, Ciau-Uitz, Aldo, Stephenson, Rachel, Patient, Roger
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5468621/
https://ncbi.nlm.nih.gov/pubmed/28584091
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1610615114
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