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Aggregation of Mod5 is affected by tRNA binding with implications for tRNA gene-mediated silencing

Mod5 is a multifunctional protein that modifies a subset of tRNAs in the cytoplasm and is also required for an RNA-mediated form of transcriptional silencing. Previous in vivo studies have shown that the nuclear silencing function of Mod5 does not require that the causative tRNA gene encode a Mod5 s...

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Veröffentlicht in:FEBS Lett
Hauptverfasser: Read, D.F., Waller, T.J., Tse, E., Southworth, D.R., Engelke, D.R., Smaldino, P.J.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2017
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5468478/
https://ncbi.nlm.nih.gov/pubmed/28303570
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/1873-3468.12627
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