Enhanced derivation of human pluripotent stem cell-derived cortical glutamatergic neurons by a small molecule

Human pluripotent stem cells (hPSCs) play important role in studying the function of human glutamatergic neurons and related disease pathogenesis. However, the current hPSC-derived cortical system produced a significant number of inhibitory GABAergic neurons that reduced the purity of excitatory neu...

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發表在:Sci Rep
Main Authors: Cao, Shi-Ying, Hu, Yao, Chen, Cheng, Yuan, Fang, Xu, Min, Li, Qi, Fang, Kai-Heng, Chen, Yaoyu, Liu, Yan
格式: Artigo
語言:Inglês
出版: Nature Publishing Group UK 2017
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Article
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC5468244/
https://ncbi.nlm.nih.gov/pubmed/28607372
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-03519-w
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