Activation of the same mGluR5 receptors in the amygdala causes divergent effects on specific versus indiscriminate fear

Although mGluR5-antagonists prevent fear and anxiety, little is known about how the same receptor in the amygdala gives rise to both. Combining in vitro and in vivo activation of mGluR5 in rats, we identify specific changes in intrinsic excitability and synaptic plasticity in basolateral amygdala ne...

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Bibliographic Details
Published in:eLife
Main Authors: Rahman, Mohammed Mostafizur, Kedia, Sonal, Fernandes, Giselle, Chattarji, Sumantra
Format: Artigo
Language:Inglês
Published: eLife Sciences Publications, Ltd 2017
Subjects:
Neuroscience
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5468087/
https://ncbi.nlm.nih.gov/pubmed/28555566
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.25665
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