mGluR2/3 in the Lateral Amygdala is Required for Fear Extinction: Cortical Input Synapses onto the Lateral Amygdala as a Target Site of the mGluR2/3 Action

Various subtypes of metabotropic glutamate receptors (mGluRs) have been implicated in fear extinction, but mGluR2/3 subtype has not been tested. Here, we found that microinjection of an mGluR2/3 antagonist, LY341495, into the lateral amygdala (LA), but not into the adjacent central amygdala (CeA), i...

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Pubblicato in:Neuropsychopharmacology
Autori principali: Kim, Jihye, An, Bobae, Kim, Jeongyeon, Park, Sewon, Park, Sungmo, Hong, Ingie, Lee, Sukwon, Park, Kyungjoon, Choi, Sukwoo
Natura: Artigo
Lingua:Inglês
Pubblicazione: Nature Publishing Group 2015
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Original Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4864627/
https://ncbi.nlm.nih.gov/pubmed/26081171
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/npp.2015.145
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