Blockade of only TGF-β 1 and 2 is sufficient to enhance the efficacy of vaccine and PD-1 checkpoint blockade immunotherapy

Checkpoint inhibition has established immunotherapy as a major modality of cancer treatment. However, the success of cancer immunotherapy is still limited as immune regulation of tumor immunity is very complicated and mechanisms involved may also differ among cancer types. Beside checkpoints, other...

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Bibliographic Details
Published in:Oncoimmunology
Main Authors: Terabe, Masaki, Robertson, Faith C., Clark, Katharine, De Ravin, Emma, Bloom, Anja, Venzon, David J., Kato, Shingo, Mirza, Amer, Berzofsky, Jay A.
Format: Artigo
Language:Inglês
Published: Taylor & Francis 2017
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Original Research
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5467996/
https://ncbi.nlm.nih.gov/pubmed/28638730
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/2162402X.2017.1308616
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