Blockade of only TGF-β 1 and 2 is sufficient to enhance the efficacy of vaccine and PD-1 checkpoint blockade immunotherapy

Checkpoint inhibition has established immunotherapy as a major modality of cancer treatment. However, the success of cancer immunotherapy is still limited as immune regulation of tumor immunity is very complicated and mechanisms involved may also differ among cancer types. Beside checkpoints, other...

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Detalhes bibliográficos
Publicado no:Oncoimmunology
Main Authors: Terabe, Masaki, Robertson, Faith C., Clark, Katharine, De Ravin, Emma, Bloom, Anja, Venzon, David J., Kato, Shingo, Mirza, Amer, Berzofsky, Jay A.
Formato: Artigo
Idioma:Inglês
Publicado em: Taylor & Francis 2017
Assuntos:
Original Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5467996/
https://ncbi.nlm.nih.gov/pubmed/28638730
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/2162402X.2017.1308616
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