Blockade of only TGF-β 1 and 2 is sufficient to enhance the efficacy of vaccine and PD-1 checkpoint blockade immunotherapy

Checkpoint inhibition has established immunotherapy as a major modality of cancer treatment. However, the success of cancer immunotherapy is still limited as immune regulation of tumor immunity is very complicated and mechanisms involved may also differ among cancer types. Beside checkpoints, other...

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Vydáno v:Oncoimmunology
Hlavní autoři: Terabe, Masaki, Robertson, Faith C., Clark, Katharine, De Ravin, Emma, Bloom, Anja, Venzon, David J., Kato, Shingo, Mirza, Amer, Berzofsky, Jay A.
Médium: Artigo
Jazyk:Inglês
Vydáno: Taylor & Francis 2017
Témata:
Original Research
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5467996/
https://ncbi.nlm.nih.gov/pubmed/28638730
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/2162402X.2017.1308616
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