Blockade of only TGF-β 1 and 2 is sufficient to enhance the efficacy of vaccine and PD-1 checkpoint blockade immunotherapy

Checkpoint inhibition has established immunotherapy as a major modality of cancer treatment. However, the success of cancer immunotherapy is still limited as immune regulation of tumor immunity is very complicated and mechanisms involved may also differ among cancer types. Beside checkpoints, other...

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Publicat a:Oncoimmunology
Autors principals: Terabe, Masaki, Robertson, Faith C., Clark, Katharine, De Ravin, Emma, Bloom, Anja, Venzon, David J., Kato, Shingo, Mirza, Amer, Berzofsky, Jay A.
Format: Artigo
Idioma:Inglês
Publicat: Taylor & Francis 2017
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Original Research
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5467996/
https://ncbi.nlm.nih.gov/pubmed/28638730
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/2162402X.2017.1308616
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