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Overexpression and Knockdown of Hypoxia-Inducible Factor 1 Disrupt the Expression of Steroidogenic Enzyme Genes and Early Embryonic Development in Zebrafish

Hypoxia is an important environmental stressor leading to endocrine disruption and reproductive impairment in fish. Although the hypoxia-inducible factor 1 (HIF-1) is known to regulate the transcription of various genes mediating oxygen homeostasis, its role in modulating steroidogenesis-related gen...

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Publicado en:Gene Regul Syst Bio
Main Authors: Tan, Tianfeng, Yu, Richard Man Kit, Wu, Rudolf Shiu Sun, Kong, Richard Yuen Chong
Formato: Artigo
Idioma:Inglês
Publicado: SAGE Publications 2017
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC5467919/
https://ncbi.nlm.nih.gov/pubmed/28634424
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1177/1177625017713193
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