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Induction of adaptive immunity leads to nigrostriatal disease progression in MPTP mouse model of Parkinson’s disease

Although 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) mouse model is the most widely-used animal model for Parkinson’s disease (PD), it is known that nigrostriatal pathologies do not persist in acute MPTP mouse model. This study highlights the importance of adaptive immunity in driving persis...

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Detaylı Bibliyografya
Yayımlandı:J Immunol
Asıl Yazarlar: Chandra, Goutam, Roy, Avik, Rangasamy, Suresh B., Pahan, Kalipada
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 2017
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC5467696/
https://ncbi.nlm.nih.gov/pubmed/28446566
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1700149
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