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Induction of adaptive immunity leads to nigrostriatal disease progression in MPTP mouse model of Parkinson’s disease
Although 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) mouse model is the most widely-used animal model for Parkinson’s disease (PD), it is known that nigrostriatal pathologies do not persist in acute MPTP mouse model. This study highlights the importance of adaptive immunity in driving persis...
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| Publicado no: | J Immunol |
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| Main Authors: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2017
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5467696/ https://ncbi.nlm.nih.gov/pubmed/28446566 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1700149 |
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