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Induction of adaptive immunity leads to nigrostriatal disease progression in MPTP mouse model of Parkinson’s disease

Although 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) mouse model is the most widely-used animal model for Parkinson’s disease (PD), it is known that nigrostriatal pathologies do not persist in acute MPTP mouse model. This study highlights the importance of adaptive immunity in driving persis...

पूर्ण विवरण

में बचाया:
ग्रंथसूची विवरण
में प्रकाशित:J Immunol
मुख्य लेखकों: Chandra, Goutam, Roy, Avik, Rangasamy, Suresh B., Pahan, Kalipada
स्वरूप: Artigo
भाषा:Inglês
प्रकाशित: 2017
विषय:
ऑनलाइन पहुंच:https://ncbi.nlm.nih.gov/pmc/articles/PMC5467696/
https://ncbi.nlm.nih.gov/pubmed/28446566
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1700149
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