Hemoglobin-Based Oxygen Carriers Promote Systemic Hyperfibrinolysis That is Both Dependent and Independent of Plasmin

BACKGROUND: Hyperfibrinolysis plays an integral role in the genesis of trauma-induced coagulopathy (TIC). Recent data demonstrates that red blood cell (RBC) lysis promotes fibrinolysis; however, the mechanism is unclear. Hemoglobin-based oxygen carriers (HBOC) have been developed for resuscitation a...

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Detalhes bibliográficos
Publicado no:J Surg Res
Main Authors: Morton, Alexander P, Moore, Ernest E, Moore, Hunter B, Gonzalez, Eduardo, Chapman, Michael P, Peltz, Erik, Banerjee, Anirban, Silliman, Christopher
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5467451/
https://ncbi.nlm.nih.gov/pubmed/28601310
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jss.2015.04.077
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