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Pleiotropic Effects of Statins on the Cardiovascular System

The 3-hydroxy-methylglutaryl coenzyme A reductase inhibitors (statins), have been used for thirty years to prevent coronary artery disease and stroke. Their primary mechanism of action is the lowering of serum cholesterol through inhibiting hepatic cholesterol biosynthesis thereby upregulating the h...

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Bibliografiske detaljer
Udgivet i:Circ Res
Main Authors: Oesterle, Adam, Laufs, Ulrich, Liao, James K
Format: Artigo
Sprog:Inglês
Udgivet: 2017
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5467317/
https://ncbi.nlm.nih.gov/pubmed/28057795
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/CIRCRESAHA.116.308537
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