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Pleiotropic Effects of Statins on the Cardiovascular System

The 3-hydroxy-methylglutaryl coenzyme A reductase inhibitors (statins), have been used for thirty years to prevent coronary artery disease and stroke. Their primary mechanism of action is the lowering of serum cholesterol through inhibiting hepatic cholesterol biosynthesis thereby upregulating the h...

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Bibliografische gegevens
Gepubliceerd in:Circ Res
Hoofdauteurs: Oesterle, Adam, Laufs, Ulrich, Liao, James K
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2017
Onderwerpen:
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5467317/
https://ncbi.nlm.nih.gov/pubmed/28057795
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/CIRCRESAHA.116.308537
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