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Pleiotropic Effects of Statins on the Cardiovascular System

The 3-hydroxy-methylglutaryl coenzyme A reductase inhibitors (statins), have been used for thirty years to prevent coronary artery disease and stroke. Their primary mechanism of action is the lowering of serum cholesterol through inhibiting hepatic cholesterol biosynthesis thereby upregulating the h...

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Detalhes bibliográficos
Publicado no:Circ Res
Main Authors: Oesterle, Adam, Laufs, Ulrich, Liao, James K
Formato: Artigo
Idioma:Inglês
Publicado em: 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5467317/
https://ncbi.nlm.nih.gov/pubmed/28057795
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/CIRCRESAHA.116.308537
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