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Pleiotropic Effects of Statins on the Cardiovascular System

The 3-hydroxy-methylglutaryl coenzyme A reductase inhibitors (statins), have been used for thirty years to prevent coronary artery disease and stroke. Their primary mechanism of action is the lowering of serum cholesterol through inhibiting hepatic cholesterol biosynthesis thereby upregulating the h...

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Publicat a:Circ Res
Autors principals: Oesterle, Adam, Laufs, Ulrich, Liao, James K
Format: Artigo
Idioma:Inglês
Publicat: 2017
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5467317/
https://ncbi.nlm.nih.gov/pubmed/28057795
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/CIRCRESAHA.116.308537
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