Antibody 10-1074 suppresses viremia in HIV-1-infected individuals

Monoclonal antibody 10-1074 targets the V3 glycan supersite on the HIV-1 envelope protein. It is among the most potent anti-HIV-1 neutralizing antibodies isolated to date. Here we report on its safety and activity in 33 subjects who received a single intravenous infusion of the antibody. 10-1074 was...

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محفوظ في:
التفاصيل البيبلوغرافية
الحاوية / القاعدة:Nat Med
المؤلفون الرئيسيون: Caskey, Marina, Schoofs, Till, Gruell, Henning, Settler, Allison, Karagounis, Theodora, Kreider, Edward F., Murrell, Ben, Pfeifer, Nico, Nogueira, Lilian, Oliveira, Thiago Y., Learn, Gerald H., Cohen, Yehuda Z., Lehmann, Clara, Gillor, Daniel, Shimeliovich, Irina, Unson-O’Brien, Cecilia, Weiland, Daniela, Robles, Alexander, Kümmerle, Tim, Wyen, Christoph, Levin, Rebeka, Witmer-Pack, Maggi, Eren, Kemal, Ignacio, Caroline, Kiss, Szilard, West, Anthony P., Mouquet, Hugo, Zingman, Barry S., Gulick, Roy M., Keler, Tibor, Bjorkman, Pamela J., Seaman, Michael S., Hahn, Beatrice H., Fätkenheuer, Gerd, Schlesinger, Sarah J., Nussenzweig, Michel C., Klein, Florian
التنسيق: Artigo
اللغة:Inglês
منشور في: 2017
الموضوعات:
Article
الوصول للمادة أونلاين:https://ncbi.nlm.nih.gov/pmc/articles/PMC5467219/
https://ncbi.nlm.nih.gov/pubmed/28092665
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nm.4268
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