Antibody 10-1074 suppresses viremia in HIV-1-infected individuals

Monoclonal antibody 10-1074 targets the V3 glycan supersite on the HIV-1 envelope protein. It is among the most potent anti-HIV-1 neutralizing antibodies isolated to date. Here we report on its safety and activity in 33 subjects who received a single intravenous infusion of the antibody. 10-1074 was...

Descrizione completa

Salvato in:
Dettagli Bibliografici
Pubblicato in:Nat Med
Autori principali: Caskey, Marina, Schoofs, Till, Gruell, Henning, Settler, Allison, Karagounis, Theodora, Kreider, Edward F., Murrell, Ben, Pfeifer, Nico, Nogueira, Lilian, Oliveira, Thiago Y., Learn, Gerald H., Cohen, Yehuda Z., Lehmann, Clara, Gillor, Daniel, Shimeliovich, Irina, Unson-O’Brien, Cecilia, Weiland, Daniela, Robles, Alexander, Kümmerle, Tim, Wyen, Christoph, Levin, Rebeka, Witmer-Pack, Maggi, Eren, Kemal, Ignacio, Caroline, Kiss, Szilard, West, Anthony P., Mouquet, Hugo, Zingman, Barry S., Gulick, Roy M., Keler, Tibor, Bjorkman, Pamela J., Seaman, Michael S., Hahn, Beatrice H., Fätkenheuer, Gerd, Schlesinger, Sarah J., Nussenzweig, Michel C., Klein, Florian
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2017
Soggetti:
Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5467219/
https://ncbi.nlm.nih.gov/pubmed/28092665
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nm.4268
Tags: Aggiungi Tag
Nessun Tag, puoi essere il primo ad aggiungerne! !

Documenti analoghi