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A molecular portrait of microsatellite instability across multiple cancers

Microsatellite instability (MSI) refers to the hypermutability of short repetitive sequences in the genome caused by impaired DNA mismatch repair. Although MSI has been studied for decades, large amounts of sequencing data now available allows us to examine the molecular fingerprints of MSI in great...

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Detalhes bibliográficos
Publicado no:Nat Commun
Main Authors: Cortes-Ciriano, Isidro, Lee, Sejoon, Park, Woong-Yang, Kim, Tae-Min, Park, Peter J.
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5467167/
https://ncbi.nlm.nih.gov/pubmed/28585546
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms15180
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