A Two-Phase Expansion Protocol Combining Interleukin (IL)-15 and IL-21 Improves Natural Killer Cell Proliferation and Cytotoxicity against Rhabdomyosarcoma

Rhabdomyosarcoma (RMS) is the most common soft tissue malignancy in children. Despite intensive research in recent decades the prognosis for patients with metastatic or relapsed diseases has hardly improved. New therapeutic concepts in anti-tumor therapy aim to modulate the patient’s immune system t...

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Detalhes bibliográficos
Publicado no:Front Immunol
Main Authors: Wagner, Juliane, Pfannenstiel, Viktoria, Waldmann, Anja, Bergs, Judith W. J., Brill, Boris, Huenecke, Sabine, Klingebiel, Thomas, Rödel, Franz, Buchholz, Christian J., Wels, Winfried S., Bader, Peter, Ullrich, Evelyn
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2017
Assuntos:
Immunology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5466991/
https://ncbi.nlm.nih.gov/pubmed/28659917
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2017.00676
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