The β-d-Endoglucuronidase Heparanase Is a Danger Molecule That Drives Systemic Inflammation and Correlates with Clinical Course after Open and Endovascular Thoracoabdominal Aortic Aneurysm Repair: Lessons Learnt from Mice and Men

Thoracoabdominal aortic aneurysm (TAAA) is a highly lethal disorder requiring open or endovascular TAAA repair, both of which are rare, but extensive and complex surgical procedures associated with a significant systemic inflammatory response and high post-operative morbidity and mortality. Heparana...

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Detalhes bibliográficos
Publicado no:Front Immunol
Main Authors: Martin, Lukas, Gombert, Alexander, Chen, Jianmin, Liebens, Julia, Verleger, Julia, Kalder, Johannes, Marx, Gernot, Jacobs, Michael, Thiemermann, Christoph, Schuerholz, Tobias
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2017
Assuntos:
Immunology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5466949/
https://ncbi.nlm.nih.gov/pubmed/28659919
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2017.00681
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