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Selective inhibition of p97 by chlorinated analogues of dehydrocurvularin()

The ATPase p97 is a ubiquitin targeted segregase that uses the energy of ATP binding and hydrolysis to extract ubiquitylated substrates from biological membranes, from other proteins, or from protein complexes to carry out myriad tasks in eukaryotes. Increased p97 activity has been linked to a poor...

Täydet tiedot

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Bibliografiset tiedot
Julkaisussa:Org Biomol Chem
Päätekijät: Tillotson, Joseph, Bashyal, Bharat P., Kang, MinJin, Shi, Taoda, De La Cruz, Fabian, Leslie Gunatilaka, A. A., Chapman, Eli
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: 2016
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC5466822/
https://ncbi.nlm.nih.gov/pubmed/27223265
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c6ob00560h
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