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Selective inhibition of p97 by chlorinated analogues of dehydrocurvularin()
The ATPase p97 is a ubiquitin targeted segregase that uses the energy of ATP binding and hydrolysis to extract ubiquitylated substrates from biological membranes, from other proteins, or from protein complexes to carry out myriad tasks in eukaryotes. Increased p97 activity has been linked to a poor...
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| 出版年: | Org Biomol Chem |
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| 主要な著者: | , , , , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
2016
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5466822/ https://ncbi.nlm.nih.gov/pubmed/27223265 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c6ob00560h |
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