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Multiphasic Regulation of Systemic and Peripheral Organ Metabolic Responses to Cardiac Hypertrophy
BACKGROUND: Reduced fat oxidation in hypertrophied hearts coincides with a shift of carnitine palmitoyl transferase I from muscle (CPT1b) to increased liver (CPT1a) isoforms. Acutely increased CPT1a in normal rodent hearts has been shown to recapitulate the reduced fat oxidation and elevated ANP mes...
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Pubblicato in: | Circ Heart Fail |
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Autori principali: | , , , , , , , , , |
Natura: | Artigo |
Lingua: | Inglês |
Pubblicazione: |
2017
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Soggetti: | |
Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5466817/ https://ncbi.nlm.nih.gov/pubmed/28404627 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/CIRCHEARTFAILURE.117.003864 |
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