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Understanding the Molecular Basis for Multiple Mitochondrial Dysfunctions Syndrome 1 (MMDS1) - Impact of a Disease-Causing Gly208Cys Substitution on Structure and Activity of NFU1 in the Fe/S Cluster Biosynthetic Pathway

Iron-sulfur (Fe/S) cluster-containing proteins constitute one of the largest protein classes, with varied functions that include electron transport, regulation of gene expression, substrate binding and activation, and radical generation. Consequently, the biosynthetic machinery for Fe/S clusters is...

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Bibliografske podrobnosti
izdano v:J Mol Biol
Main Authors: Wachnowsky, Christine, Wesley, Nathaniel A., Fidai, Insiya, Cowan, J. A.
Format: Artigo
Jezik:Inglês
Izdano: 2017
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC5466808/
https://ncbi.nlm.nih.gov/pubmed/28161430
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jmb.2017.01.021
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