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Understanding the Molecular Basis for Multiple Mitochondrial Dysfunctions Syndrome 1 (MMDS1): Impact of a Disease-Causing Gly189Arg Substitution on NFU1

Iron-sulfur (Fe/S) cluster-containing proteins constitute one of the largest protein classes, with highly-varied function. Consequently, the biosynthesis of Fe/S clusters is evolutionarily conserved and mutations in intermediate Fe/S cluster scaffold proteins can cause disease, including multiple mi...

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Detalhes bibliográficos
Publicado no:FEBS J
Main Authors: Wesley, Nathaniel A., Wachnowsky, Christine, Fidai, Insiya, Cowan, J. A.
Formato: Artigo
Idioma:Inglês
Publicado em: 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5696030/
https://ncbi.nlm.nih.gov/pubmed/28906594
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/febs.14271
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