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Pharmacovigilance database search discloses ClC‐K channels as a novel target of the AT(1) receptor blockers valsartan and olmesartan
BACKGROUND AND PURPOSE: Human ClC‐K chloride channels are highly attractive targets for drug discovery as they have a variety of important physiological functions and are associated with genetic disorders. These channels are crucial in the kidney as they control chloride reabsorption and water diure...
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| Publicado no: | Br J Pharmacol |
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| Main Authors: | , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
John Wiley and Sons Inc.
2017
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5466521/ https://ncbi.nlm.nih.gov/pubmed/28334417 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/bph.13794 |
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