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The analgesic and anti-inflammatory effects of Salvinorin A analogue β-tetrahydropyran Salvinorin B in mice

BACKGROUND: Drugs activating the mu opioid receptor are routinely used to treat severe acute and chronic pain. Unfortunately, side effects including nausea, constipation, respiratory depression, addiction and tolerance can limit clinical utility. In contrast, kappa opioid receptor (KOPr) agonists, s...

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Bibliografiske detaljer
Udgivet i:Eur J Pain
Main Authors: Paton, K.F., Kumar, N., Crowley, R.S., Harper, J.L., Prisinzano, T.E., Kivell, B.M.
Format: Artigo
Sprog:Inglês
Udgivet: 2017
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5466480/
https://ncbi.nlm.nih.gov/pubmed/28158929
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/ejp.1002
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