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Inhibition of eicosanoid biosynthesis by glucocorticoids in humans.

Therapeutic doses of glucocorticoids are thought to inhibit prostaglandin and leukotriene formation in humans. Several studies in animals, however, have failed to demonstrate modulation of eicosanoid biosynthesis by steroids in vivo. We administered prednisone (60 mg/day) to eight healthy volunteers...

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Udgivet i:Proc Natl Acad Sci U S A
Principais autores: Sebaldt, R J, Sheller, J R, Oates, J A, Roberts, L J, FitzGerald, G A
Format: Artigo
Sprog:Inglês
Udgivet: National Academy of Sciences 1990
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC54664/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2169616/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.87.18.6974
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