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Inhibition of eicosanoid biosynthesis by glucocorticoids in humans.

Therapeutic doses of glucocorticoids are thought to inhibit prostaglandin and leukotriene formation in humans. Several studies in animals, however, have failed to demonstrate modulation of eicosanoid biosynthesis by steroids in vivo. We administered prednisone (60 mg/day) to eight healthy volunteers...

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Détails bibliographiques
Publié dans:Proc Natl Acad Sci U S A
Auteurs principaux: Sebaldt, R J, Sheller, J R, Oates, J A, Roberts, L J, FitzGerald, G A
Format: Artigo
Langue:Inglês
Publié: National Academy of Sciences 1990
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Accès en ligne:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC54664/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2169616/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.87.18.6974
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