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Biosynthetic Origin of the Ether Ring in Platensimycin
Platensimycin (PTM) and platencin (PTN) are highly functionalized bacterial diterpenoid natural products that target bacterial and mammalian fatty acid synthases. PTM and PTN feature varying diterpene-derived ketolides that are linked to the same 3-amino-2,4-dihydroxybenzoic acid moiety. As a result...
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| Udgivet i: | J Am Chem Soc |
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| Main Authors: | , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2016
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5466352/ https://ncbi.nlm.nih.gov/pubmed/27966343 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jacs.6b09818 |
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