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Vaccination with a Leishmania infantum HSP70-II null mutant confers long-term protective immunity against Leishmania major infection in two mice models
BACKGROUND: The immunization with genetically attenuated Leishmania cell lines has been associated to the induction of memory and effector T cell responses against Leishmania able to control subsequent challenges. A Leishmania infantum null mutant for the HSP70-II genes has been described, possessin...
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| Pubblicato in: | PLoS Negl Trop Dis |
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| Autori principali: | , , , , , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
Public Library of Science
2017
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5466331/ https://ncbi.nlm.nih.gov/pubmed/28558043 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pntd.0005644 |
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