Vaccination with a Leishmania infantum HSP70-II null mutant confers long-term protective immunity against Leishmania major infection in two mice models

BACKGROUND: The immunization with genetically attenuated Leishmania cell lines has been associated to the induction of memory and effector T cell responses against Leishmania able to control subsequent challenges. A Leishmania infantum null mutant for the HSP70-II genes has been described, possessin...

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Detalhes bibliográficos
Publicado no:PLoS Negl Trop Dis
Main Authors: Solana, José Carlos, Ramírez, Laura, Corvo, Laura, de Oliveira, Camila Indiani, Barral-Netto, Manoel, Requena, José María, Iborra, Salvador, Soto, Manuel
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2017
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5466331/
https://ncbi.nlm.nih.gov/pubmed/28558043
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pntd.0005644
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