Leishmania infantum HSP70-II null mutant as candidate vaccine against leishmaniasis: a preliminary evaluation

BACKGROUND: Visceral leishmaniasis is the most severe form of leishmaniasis and no effective vaccine exists. The use of live attenuated vaccines is emerging as a promising vaccination strategy. RESULTS: In this study, we tested the ability of a Leishmania infantum deletion mutant, lacking both HSP70...

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Detalhes bibliográficos
Main Authors: Carrión, Javier, Folgueira, Cristina, Soto, Manuel, Fresno, Manuel, Requena, Jose M
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2011
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3199857/
https://ncbi.nlm.nih.gov/pubmed/21794145
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1756-3305-4-150
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