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Improving the biophysical properties of anti-ricin single-domain antibodies()

Single-domain antibodies (sdAbs) derived from heavy-chain only antibodies produced in camelids are attractive immunoreagents due to their small size, high affinity, and ability to refold and retain binding activity after denaturation. It has been observed that some sdAbs, however, exhibit undesirabl...

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Detalhes bibliográficos
Publicado no:Biotechnol Rep (Amst)
Main Authors: Turner, Kendrick B., Liu, Jinny L., Zabetakis, Dan, Lee, Audrey Brozozog, Anderson, George P., Goldman, Ellen R.
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5466252/
https://ncbi.nlm.nih.gov/pubmed/28626694
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.btre.2015.01.001
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