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Improving the biophysical properties of anti-ricin single-domain antibodies()

Single-domain antibodies (sdAbs) derived from heavy-chain only antibodies produced in camelids are attractive immunoreagents due to their small size, high affinity, and ability to refold and retain binding activity after denaturation. It has been observed that some sdAbs, however, exhibit undesirabl...

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Dades bibliogràfiques
Publicat a:Biotechnol Rep (Amst)
Autors principals: Turner, Kendrick B., Liu, Jinny L., Zabetakis, Dan, Lee, Audrey Brozozog, Anderson, George P., Goldman, Ellen R.
Format: Artigo
Idioma:Inglês
Publicat: Elsevier 2015
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5466252/
https://ncbi.nlm.nih.gov/pubmed/28626694
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.btre.2015.01.001
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