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Multicomponent mixtures for cryoprotection and ligand solubilization()
Mixed cryoprotectants have been developed for the solubilization of ligands for crystallization of protein–ligand complexes and for crystal soaking. Low affinity lead compounds with poor solubility are problematic for structural studies. Complete ligand solubilization is required for co-crystallizat...
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| Publicado no: | Biotechnol Rep (Amst) |
|---|---|
| Main Authors: | , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Elsevier
2015
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5466044/ https://ncbi.nlm.nih.gov/pubmed/28626721 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.btre.2015.05.008 |
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