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The application of the Escherichia coli giant spheroplast for drug screening with automated planar patch clamp system

Kv2.1, the voltage-gated ion channel, is ubiquitously expressed in variety of tissues and dysfunction of this ion channel is responsible for multiple diseases. Electrophysiological properties of ion channels are so far characterized with eukaryotic cells using the manual patch clamp which requires s...

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Библиографические подробности
Опубликовано в: :Biotechnol Rep (Amst)
Главные авторы: Kikuchi, Kyoko, Sugiura, Mika, Nishizawa-Harada, Chizuko, Kimura, Tadashi
Формат: Artigo
Язык:Inglês
Опубликовано: Elsevier 2015
Предметы:
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC5466043/
https://ncbi.nlm.nih.gov/pubmed/28626710
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.btre.2015.04.007
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