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High Proteolytic Resistance of Spider-Derived Inhibitor Cystine Knots
Proteolytic stability in gastrointestinal tract and blood plasma is the major obstacle for oral peptide drug development. Inhibitor cystine knots (ICKs) are linear cystine knot peptides which have multifunctional properties and could become promising drug scaffolds. ProTx-I, ProTx-II, GTx1-15, and G...
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| Pubblicato in: | Int J Pept |
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| Autori principali: | , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
Hindawi Publishing Corporation
2015
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4710912/ https://ncbi.nlm.nih.gov/pubmed/26843868 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2015/537508 |
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