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High Proteolytic Resistance of Spider-Derived Inhibitor Cystine Knots
Proteolytic stability in gastrointestinal tract and blood plasma is the major obstacle for oral peptide drug development. Inhibitor cystine knots (ICKs) are linear cystine knot peptides which have multifunctional properties and could become promising drug scaffolds. ProTx-I, ProTx-II, GTx1-15, and G...
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| Publicado no: | Int J Pept |
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| Main Authors: | , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Hindawi Publishing Corporation
2015
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4710912/ https://ncbi.nlm.nih.gov/pubmed/26843868 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2015/537508 |
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