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High Proteolytic Resistance of Spider-Derived Inhibitor Cystine Knots

Proteolytic stability in gastrointestinal tract and blood plasma is the major obstacle for oral peptide drug development. Inhibitor cystine knots (ICKs) are linear cystine knot peptides which have multifunctional properties and could become promising drug scaffolds. ProTx-I, ProTx-II, GTx1-15, and G...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Julkaisussa:Int J Pept
Päätekijät: Kikuchi, Kyoko, Sugiura, Mika, Kimura, Tadashi
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Hindawi Publishing Corporation 2015
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC4710912/
https://ncbi.nlm.nih.gov/pubmed/26843868
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2015/537508
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