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The Topology of Bulges in the Long Stem of the Flavivirus 3′ Stem-Loop Is a Major Determinant of RNA Replication Competence

All flavivirus genomes contain a 3′terminal stem-loop secondary structure (3′SL) formed by the most downstream ∼100 nucleotides (nt) of the viral RNA. The 3′SL is required for virus replication and has been shown to bind both virus-coded and cellular proteins. Results of the present study using an i...

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Detalles Bibliográficos
Main Authors: Yu, Li, Markoff, Lewis
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Microbiology 2005
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC546603/
https://ncbi.nlm.nih.gov/pubmed/15681432
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.79.4.2309-2324.2005
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