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Specific requirements for elements of the 5' and 3' terminal regions in flavivirus RNA synthesis and viral replication

We initially studied requirements for 5' and 3' terminal regions (TRs) in flavivirus negative strand synthesis in vitro. Purified West Nile (WNV) and dengue-2 (DV2) RNA polymerases were both active with all-WNV or all-DV2 subgenomic RNAs containing the 5'- and 3'TRs of the respec...

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Autori principali: Yu, Li, Nomaguchi, Masako, Padmanabhan, R., Markoff, Lewis
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2008
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3368002/
https://ncbi.nlm.nih.gov/pubmed/18234265
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.virol.2007.12.035
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