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Rapid Detection and Quantitation of BRAF Mutations in Hairy Cell Leukemia Using a Sensitive Pyrosequencing Assay
BRAF proto-oncogene is an important mediator of cell proliferation and survival signals via the RAS-RAF-MEK-ERK signaling pathway. BRAF p.V600E mutation was recently described as a molecular marker of hairy cell leukemia (HCL). We developed and validated a pyrosequencing-based approach that covers B...
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出版年: | Am J Clin Pathol |
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主要な著者: | , , , , , , , , , , |
フォーマット: | Artigo |
言語: | Inglês |
出版事項: |
2012
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主題: | |
オンライン・アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5465956/ https://ncbi.nlm.nih.gov/pubmed/22706871 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1309/AJCPL0OPXI9LZITV |
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