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EHD2 restrains dynamics of caveolae by an ATP-dependent, membrane-bound, open conformation
The EH-domain–containing protein 2 (EHD2) is a dynamin-related ATPase that confines caveolae to the cell surface by restricting the scission and subsequent endocytosis of these membrane pits. For this, EHD2 is thought to first bind to the membrane, then to oligomerize, and finally to detach, in a st...
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| Udgivet i: | Proc Natl Acad Sci U S A |
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| Main Authors: | , , , , , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
National Academy of Sciences
2017
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5465919/ https://ncbi.nlm.nih.gov/pubmed/28223496 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1614066114 |
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