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Loss of the homologous recombination gene rad51 leads to Fanconi anemia-like symptoms in zebrafish
RAD51 is an indispensable homologous recombination protein, necessary for strand invasion and crossing over. It has recently been designated as a Fanconi anemia (FA) gene, following the discovery of two patients carrying dominant-negative mutations. FA is a hereditary DNA-repair disorder characteriz...
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| Publicado no: | Proc Natl Acad Sci U S A |
|---|---|
| Main Authors: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
2017
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5465903/ https://ncbi.nlm.nih.gov/pubmed/28512217 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1620631114 |
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